49ers vs Titans Thursday Night Football Picks and Predictions: Niners Keep Rolling in Tennessee

This week’s Thursday Night Football matchup features a pair of teams trending in completely opposite directions with their postseason hopes hanging in the balance.

The San Francisco 49ers have won five of six to climb into the sixth spot in the NFC while the Tennessee Titans’ hold on the top spot in the AFC South suddenly looks tenuous after losing three of four.

But are the Titans a live home dog? Find out in our free NFL betting picks and predictions for 49ers vs. Titans on Thursday, December 23.